Prof. Dr. M. A. Haleem

Professor Emeritus
(Life Time)



[email protected]



(021) 34988000

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https://linkedin.com/

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Online Publications

Department (s)

Education

Ph.D.
Biophysics
Leeds Univ. U.K. 1971

M.Sc.
Karachi University -1965

B.Sc. (Hons)
Karachi University – 1964

Awards & Honors

List honors or awards for scholarship or professional activity.

1.PhD thesis Title : X-ray diffraction studies on the structure of alpha-chitin and β-D-1,3 xylan , University of Leeds (UK) -1971

2.Research Award:

. I was awarded common wealth Scholarship (1968-1971)

Received Karachi University research award (1997-1998)
Awarded presidential award of academic distinction “Eizaz-Fazelat” 2002.

3.Received research productivity allowance for the year 2000-2001 PCST

4.Research grants:

Pakistan Science Foundation Research Grant (1975-1977).
NSRDB Research Grant (UGC) (1990-1993)
Karachi University Research Grants (1983-1984) and

(1986-2001)

Selected by PCST to supervise PhD level research.

Research :

Research publications are more than 122 in national and international journals

Memberships

Pakistan Standards and Quality Control Authority Standards

Development Centre.

Member Board of advance studies and research SSUET.
Member Board of Faculty of computing and applied sciences SSUET
Member Board of Faculty of Electrical Engineering SSUET
Member Board of Faculty Of Engineering Barret Hodgson University.Karachi
Member Academic Council, Sir syed Univ. of Engineering

And Technology (SSUET)

Chairman Research Project, Department of Biomedical

Engineering (2003-2017)

7.Convenor Library Committee, SSUET

Member HEC Curriculum Biochemistry (2002)
Secretary HEC Curriculum Committee of Biomedical

Engineering Department (2008)

Convenor HEC of Curriculum Committee of Biomedical

Engineering Department (2012)

Member Advisory Committee Golden Jubilee Celebrations of

Biochemistry Department (2012)

Editor and former editor In Chief Sir Syed University

Research Journal of Engineering of Technology Published b

Sir Syed University of Engineering of Technology

Editor and former Editor In Chief of News Letter Published

by Sir Syed University of Engineering of Technology 1.Life

member Pakistan Society of Biochemists

Member of Pakistan Pharmacological Society

Biography

Department: Biomedical Engineering (SSUET)
Professor-(2003-2019)/Chairman (2003-2017)
Electronic Engineering Dept.(SSUET)
Prof. and Chairman (6 months)
Dept of Bioinformatics :
Prof. and Acting Chairman (2017-2021)

Publications

Fasting leptin and glucose in normal weight, over weight and obese men and women diabetes patients with and without clinical depression.(2017)
Haleem DJ, Sheikh S, Fawad A, Haleem MA.(2017)
Metab Brain Dis. Jun;32(3):757-764
Impact factor:3.765

Inhibition of hormonal and behavioral effects of stress by tryptophan in rats.
Gul S, Saleem D, Haleem MA, Haleem DJ.
Nutr Neurosci. Nov 3:1-9
Impact factor:2.297

Noreen Samad , Muhammad Abdul Haleem and Darakhshan Jabeen Haleem (2016)
Pak.J.Pharm. Sci.29(4) :1467-1471
0.682 Impact Factor

Darakhshan J Haleem · Qurrat-Ul-Aen Inam · Saida Haider · Tahira Perveen · Muhammad Abdul Haleem · (2015)

Serum Leptin and Cortisol, Related to Acutely Perceived Academic Examination Stress and Performance in Female University Students Applied Psychophysiology and Biofeedback 40(4);305-12
1.13 Impact Factor

S. M. Omair, Nageen Shahid, M. A. Haleem, M. Azam, M. W. Munir and M. Z. ul Haque (2014)
Fluid Dispense Prototype: A time Based Approach. SSUET Research Journal of Engineering & Technology Vol 4 (1): 21-25

Darakhshan Jabeen Haleem · Huma Ikram · Muhammad Abdul Haleem ·(2014)
Inhibition of Apomorphine-induced Conditioned Place Preference in Rats Co-injected with Buspirone: Relationship with Serotonin and Dopamine in the Striatum
Brain Research 10/2014; 1586. DOI:10.1016/j.brainres.2014.06.022 ·
2.84 Impact Factor

Darakhshan J. Haleem · Zeba Haque · Huma Ikram · Muhammad A. Haleem · (2014)

Leptin and other Hormonal Responses to Different Stressors: Relationship with Stress-Induced Behavioral Deficits.

Pakistan Veterinary Journal 06/2014; 34(4):504-507. · 1.39 Impact Factor

Darakhshan Jabeen Haleem · Huma Ikram · Saida Haider · Tahira Parveen · Muhammad Abdul Haleem ·(2013)

Enhancement And Inhibition of Apomorphine-induced Sensitization in Rats Exposed to Immobilization Stress: Relationship With Adaptation to Stress.

Pharmacology Biochemistry and Behavior 09/2013; 112. DOI:10.1016/j.pbb.2013.09.011 ·

2.78 Impact Factor

Ahmed W, Khan IA, Arshad MN, Siddiqui WA, Haleem MA, Azim MK (2013)

Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors.

Pak J Pharm Sci. 2013 Jul;26(4):687-90

0.682 Impact Factor

Mirza B, Ikram H, Bilgrami S, Haleem DJ, Haleem MA.

Neurochemical and behavioral effects of green tea (Camellia sinensis): a model study.

Pak J Pharm Sci. 2013 May;26(3):511-6.

0.68 Impact Factor

Haque Z, Akbar N, Yasmin F, Haleem MA, Haleem DJ.

Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats.

Stress. 2013 May;16(3):353-62. doi: 10.3109/10253890.2012.736047. Epub 2012 Nov 5. 2.72 Impact Factor

Batool F, Haleem M.A and Haleem Darakhshan Jabeen (2010)

Acute administration of clozapine and risperidone altered dopamine metabolism more in rat caudate than nucleus accumbens: a dose related study.

Sci Pharm 78: 259-274

0.41 Impact Factor

Batool F, Hasnat A., Haleem M.A and Haleem Darakhshan Jabeen (2010)

Dose related effects of clozapine and risperidone on the pattern of brain serotonin and dopamine metabolism and on tests related to extra pyramidal functions in rats. Acta Pharm 60: 129-140

0.91 Impact Factor

Waseem A, Mubeen R, Ishtiaq AK, Asif I, Khalid MK, Haleem M. A. and Azeem M. K. (2010)

Characterization of hydrazides and hydrazine derivatives as novel aspartic protease inhibitors

Journal of Enzyme inhibition and medicinal chemistry, 25(5):673-678

2.33 Impact Factor

D. Haleem · N. Samad · F. Batool · M. A. Haleem (2009)

P2.007 Serotonergic modulation of dopamine neurotransmission: a mechanism for extending therapeutics in schizophrenia

Parkinsonism & Related Disorders 12/2009; 15. DOI:10.1016/S1353-8020(09)70358-X

3.97 Impact Factor

Inam Qurrat-Ul-Aen; Haleem M Abdul; Haleem Darakhshan Jabeen (2009)
Attenuation of somatodendritic responses to 8-hydroxy-2-di-npropylamino tetralin following long-term dietary sugar consumption in rats.Journal of the College of Physicians and Surgeons-Pakistan: JCPSP 2009;19 (7):401-5.0.95 Impact Factor

Farhat Batool · Muhammad A Haleem · Darakhshan J Haleem (2009)

Acute Administration of Clozapine and Risperidone Altered Dopamine Metabolism More in Rat Caudate than in Nucleus Accumbens: A Dose-Response Relationship

3Scientia Pharmaceutica 01/2009; 78(2):259-74. DOI:10.3797/scipharm.0907-20

0.37 impact Factor

Asma Khan, M. A. Haleem and Darkhshan J. Haleem (2008)

Dopamine and Serotonin Metabolism in the Dorsal and Ventral Striatum of Haloperidol-induced Tardive Dyskinesia Model in Rats.

J. Chem. Soc. Pak, 30 (3): 410-416.

Qurrat ul Ain Inam, M. A. Haleem and Darakhshan J. Haleem (2008)

Neurochemical profile of 8-Hydroxy-2-(Di-N-propylamino) tetralin (8-OH-DPAT) induced hyperphagia in sugar rich diet treated rats.

J. Chem. Soc. Pak, 30 (3): 431-436

Reshma Farooq, Darakhshan J. Haleem and M. A. Haleem (2008)

Dose related anxiolytic effects of diazepam: Relation with serum electrolytes, plasma osmolality and systolic blood pressure (SBP) in rats.

Pakistan Journal of Pharmacology 25 (1): 37-42

M. A. Haleem, M. Z. Haque, F. Azhar & M. A. Muqeet (2008)

Evaluation of Conversational and Non-Conversational pulse Oximetre

Antwerp. Springer Berlin Heidelberg, Vol. 22.1680-0737- German

Farzana Yasmin · Darakhshan J Haleem · M A Haleem (2007)

Effects of repeated restraint stress on serum electrolytes in ethanol-treated and water-treated ra rats.

Pakistan J. of Pharmaceutical sciences02/2007;20(1):51-5.

0.68 impact factor

Darakhshan J. Haleem, Noreen Samad, Tahira Perveen, Saida Haider and M. A.Haleem(2007)

Role of Serotonin-1A Receptors in Restraint-induced behavioral deficits and adaptation to repeated restraint stress in rats

Intern. J. Neuroscience, 117: 243-257 1.52 Impact Factor

Darakhshan J. Haleem, Noreen Samad and M. A. Haleem (2007)

Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic response by buspirone in rats.

Science Direct: Pharmacology, Biochemistry and Behavior 87: 115-121

2.78 Impact Factor

Darakhshan J. Haleem, Noreen Samad and M. A. Haleem (2007)

Reversal of haloperidol-induced extra pyramidal symptoms by buspirone: a time-related study.

Behavioral Phamacology 18: 147-153.

2.15 Impact Factor

Nooreen Samad, Asma Khan,T.Perveen,S.Haider, M.A.Haleem and Darakhshan J. Haleem (2007):

Increase in the effectiveness of somatodendritic 5-HT-1A receptors in rat model of tardive dyskinesia

Acta Neurobiol Exp .67:389-397.

1.29 Impact Factor

Reshma Farooq, Darakhshan J. Haleem and M. A. Haleem (2007):

Dose related effects of buspirone on serum electrolyte balance, plasma osmolality and systolic blood pressure (SBP) in rats.

Pak. J. Pharm. Sci., 20(4): 295-299

0.68 Impact Factor

Farzana Yasmeen,Darakhshan J Haleem and M A Haleem (2006)

Intraerythrocytes and serum electrolytes in diabetic patients with hypertension

JCPSP ,16(7) : 445-449

Noreen S.,Tahira P.,Saida Haider,M.A.Haleem and Darakhshan J Haleem(2006)

Inhibition of restraint-induced neuroendocrine and serotonergic by buspirone in rats

Pharmacological Reports 58, 636-642.

N. Samad, M.A. Haleem and D.J. Haleem(2006)

Neurochemical profile of 1-(m-Chlorophenyl)piperazine (m-CPP) in the Striatum of a Rat Model of Tardive Dyskinesia, Jour.Chem.Soc.Pak. Vol. 28, No. 6: 605-610.

Qurat-ul-Ain Imam, M. Abdul Haleem and Darakhshan Jabeen Haleem (2006)

Neurochemical and behavioral effects of 1-(3-chlorophenyl) piperazine (m-CPP) in sugar rich diet treated rats. Pakistan Journal of biochemistry and Molecular Biology Vol.39(3-4): 67-72.

Farhat Bano · Sadaf Naeem · Naheed Akhtar · M A Haleem (2005)

Computer aided conformational analysis of sulfonated azo dyes diammonium orange G (C16H10N2O7S2 (NH4) x 4H2O.

Pakistan journal of pharmaceutical sciences 08/2005; 18(3):66-70. · 0.68 Impact Factor

R. Farooq, Darakhshan J. H and T. Mehboob and M. A. Haleem (2005)

Effect of Restraint Stress on Serum Electrolytes in Rats Annals

(Abbashi Shaheed Hospital and Karachi Medical & Dental College)

10 (1): 646-649.

Darakhshan J. H, A. Hasnat, E. Shireen and M. A. Haleem (2005)

Dopamine and Serotonin Neurotransmission in the Reinforcing Effects of Alcohol and Apomorphine

JCPSP, 15 (8): 458-462

Darakhshan Jabeen Haleem, Erum Shireen and M. A. Haleem (2005)

Somatodendritic and Postsynaptic serotonin-1A receptors in the attenuation of haloperidol-induced

Catalepsy

Progress in Neuro-Psychopharmacology & Biological Psychiatry 28,1323-1329.

3.69 Impact Factor

Sadaf Naeem ,Naheed Akhtar ,Waseem Ahmed ,Farhat Bano and M.A.Haleem (2004)

Conformational Analysis of 2-(α-D-lyxofuranosyl) Maleimide

Pak.J.Pharmacol. 21(1): 31-36.

Waseem Ahmed ,N.Akhtar and M A Haleem(2004)

Conformational analysis of 2(4-(5-bromo-Methyl pyridyl)butyl amino)-4-pyrimidone

Hamdard Medicus XLVII(1): 50-53.

N.Akhtar,S.Naeem,F.Bano,W.Ahmed and M.A.Haleem(2004)

Conformational analysis of [ Pd(diethylene triamine )(guanosine)](ClO4)2

Hamadard Medicus XLVII(3): 133-135

N.Akhtar,S.Haseen ,I.M.Kidwai and M.A.Haleem(2004)

Computer aided conformational analysis of 2-Deoxy-3-5-di-o-acetyl Adenosine

Hamdard Medicus XLVII(2): 52-53.

N.Akhtar,S.Naeem,W,Ahmed and M.A.Haleem (2004)

Rigid body refinement of water mediated triple helical structure of b-D-1,.3 xylan from Palmaria Palmata (L.)Kuntze, Rhodophyta

Pak.J.Botany 36(4): 745-750.

0.82 Impact Factor

Waseem Ahmed,N.Akhtar and M A Haleem (2004)

Conformational analysis of temalastine

Karachi University J. of Science 32(1-2):1-5

Waseem Ahmed, Nahid Akhtar and M. A. Haleem (2003)

Conformational analysis of 3{4-(5-Bromo-3 methy1 pyrid-2-yl-buty1 amino)4-(benzylamino)-1,2,5- thiadiazole-1-oxide.

Pak J. Biochem and Mol. Biol 36 (1): 40-44

Obaid Ali, Darakhshan J. Haleem, Roohi Obaid, Noor Kamil, M. A. Haleem and S. Waseemuddin Ahmed (2003).

Effects of co-administration of Haloperidol and large neutral amino acids (tryptophan and valine) on rat striatal dopamine, serotonin and their metabolites. Pakistan J. of Pharmaceutical sciences.

16 (1): 13-25

Farhat Bano, Naheed Akhtar and M. A. Haleem (2003)

Computer aided conformational analysis of Pt (diethylene triamine) guanosine} (CIO4)2

Pak J. Biochem and Mol Biol 36 (1): 24-26

Darakhshan J. Haleem, F. Batool, N. Khan, N. Kamil, O. Ali Zafa S. Saify and M. A. Haleem (2002)

Differences in the effects of haloperidol and clozapine on brain serotonin and dopamine metabolism and on tests related to extrapyramidal functions in rats.

Medical Science Monitor, 8 (9): 354-361

Darakhshan J. Haleem, H. Naz, T. Perveen, S. Haider, S. Ahmed, N. Khan and M. A. Haleem (2002)

Serotonin and serotonin-1A receptors in the failure of ethanol treated rats to adapt a repeated stress

schedule. J. Studies on Alcohol, 63: 389-396

Waseem Ahmed, Naheed Akhtar and M. A. Haleem (2002)

conformational analysis of histamine H1 receptor antagonists

Pak J. Biochem and Mol Biol. 35 (2): 60-62

Darakhshan J.Haleem ,Z.S.Saify ,S. Siddiqui ,F.Batool, and M.A.Haleem (2001)

Pre and post synaptic responses to 1-(1-naphthyl–piperazine) following adaption to stress in rats.

Prog.Neuropsychopharmacol &Bio.Psychriat. 26: 149-156 (USA).

Naheed Akhtar ,Imran Aslam and M.A.Haleem (2001)

Computer aided conformational analysis of thebaine

Hamdard Medicos XLIV(1). 96-98

F Batool · Z S Saify · M A Haleem · D J Haleem (2000)

Neurochemical and extra pyramidal effects of atypical neuroleptic clozapine in rats.

Pakistan journal of pharmaceutical sciences 02/2000; 13(1):47-55. · 0.68 Impact Factor

Darakhshan J.Haleem ,Saida Haider,Thahira parveen,Qurat-ul-Ain ,I.M.Kidwai and M.A.Haleem(2000)

Hyperphagia and decreases of brain serotonin in rats fed freely on sugar rich diet for three weeks

Nutritional Neurosciences, 3:399-405

N. Akhtar, N. Fatima, I. M. Kidwai and M. A. Haleem (1999)

Computer aided conformational analysis of antihistamine drug chlorpheniramine maleate

Hamdard Medicus XIII (2): 69-71

T. Mahboob and M. A. Haleem (1997)

Probable role of tissue electrolytes in SBP elevation after long term ethanol administration in rats.

Proc. ISBBP Symp. Biochem. Biophys.2: 11-14

S. Z. Khan, J.M. Alam and M. A. Haleem (1997)

Effects of high doses of aspirin on blood parameters of male albino rats under stress and unstressed conditions

Proc. ISBBP Symp. Biochem. Biophys.2: 51-54

M. A. Haleem, N. Akhtar and M. Zehra (1997)

Conformational analysis of opiate alkaloid (7-(1-cyclohexyl-1-hydroxyethyl)-16-ethyl-6,14-endo-6,7,8,14-tetrahydro-3-oripavinyl methyl ether

Proc. ISBBP Symp. Biochem. Biophys.2: 55-57

S. Z. Khan, J. M. Alam and M. A. Haleem (1997)

Effects of high doses of aspirin in male albino rats

Proc. ISBBP Symp. Biochem. Biophys.2: 81-84

K. Saboohi, M. A. Haleem and T. Mahboob (1997)

Calcium dependent hypermagnesaemia in KCl supplemented rats

Proc. ISBBP Symp. Biochem. Biophys.2: 95-98

F. Yasmeen, D. J. Haleem and M. A. Haleem (1997)

Decreases of serum electrolytes following repeated restraint in ethanol treated rats

Proc. ISBBP Symp. Biochem. Biophys.2: 119-122

S. Z. Khan, J. M. Alam, S.R. Mahmood and M. A. Haleem (1997)

Aspirin-induced toxicity and associated hypo and hyperkalaemia

Proc. ISBBP Symp. Biochem. Biophys.2: 123-125

N. Shaheen, D. J. Haleem and M. A. Haleem (1997)

Decreases of sodium and increases of potassium concentrations following the administration of spironolactone are greater in male than female rabbits

Proc. ISBBP Symp. Biochem. Biophys.2: 165-168

Z. Fatima and M. A. Haleem (1997)

Effects of acute administration of acetazolamide on serum sodium, potassium, calcium and phosphorus: a comparative study in male and female rabbits

Proc. ISBBP Symp. Biochem. Biophys.2: 183-186

M. A. Haleem, M. Zehra, I. M. Kidwai, Z. S. Saify and N. Akhtar (1997)

Conformational analysis of histamine H-1 receptor antagonist

Proc. ISBBP Symp. Biochem. Biophys.2: 283-286

T.Mahboob, Darakhshan J.Haleem, M.Mumtaz and M.A.Haleem (1996)

Stress and hypertension: Role of serum, red cell and tissue electrolytes.

Life Science (USA) 58(18):1587-1590.

2.7 Impact Factor

Samina Bano, Darakhshan J.Haleem and M.A.Haleem (1996):

Injected monosodium glutamate increases holoenzyme pyrrolase activity and plasma corticosterone levels more in male than female rats.

Pak.J.Pharm. 13(1): 27-33.

T.Mahboob, M.Mumtaz and M.A.Haleem (1996)

Electrolyte content of serum, erythrocyte, kidney and heart tissue in salt induced hypertensive rats.

Life Sciences(USA) 59 (9): 731-737

2.7 Impact Factor

K. Saboohi, T. Mahboob, M. Mumtaz and M. A. Haleem (1995)

Effect of potassium chloride supplementation on intra and extracellular electrolytes in rats.

Pak. J. Pharmacol. 12 (2): 59-64

Darakhsahan J.Haleem ,A.Yasmeen, M.A.Haleem and A.Zafar (1995)

24 hr.withdrawl following repeated administration of caffeine attenuates brain serotonin but not trytophan in rat brain:Implifications for caffeine induced depression.

Life Science (USA) 57(19) PL285-PL292.

2.7 Impact Factor

Darakhshan J.Haleem, T.Perveen, S.Haider, A.Yasmeen ,A.Zafar,F.Batool and M.A.Haleem (1995)

Brain serotonin in the modulation of appetite by stress starvation and drugs:

Possible normalization by food.

Second Int.Conf.on the impacts of food research of new product development (Karachi) pp.30

Kahkashan Perveen and M.A.Haleem.(1995):

Studies on the structure of cellulose II.

In:Recent discoveries in natural product chemistry,

Proc.5th IUPAC Sym.on the chemistry of Nat. Products.

Ed:Attaur Rehman,M.I.Choudhary M.S.Sheikha

Karachi, Pakistan.pp345-354.

M.Ismail, N.Akhtar,I.M.Kidwai and M.A.Haleem(1995):

Potentential energy calculations of 4′-fluoro-4-[4-(2-pyridyl)-1-piperazinyl] butyrophenone (azaperone).

Kar.Uni.J.Sc.23 (1&2): 81-87.

Kahkashan Parveen and M.A.Haleem (1994)

Studies on the structure of cellulose I

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1, 24-27

M.K. Azeem, Naheed Akhter and M. A. Haleem (1994)

Computer aided conformational analysis of psychoactive agent: amoxipine

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1: 40-43.

I.M. Kidwai and M. A. Haleem (1994)

Interlayer H- bonding in α-chitin

Proc.ISBBP Symposium Biochem.Biophysics (Karachi) 1, 56-58

I. Sabah, K. Parveen and M. A. Haleem (1994)

Potential energy calculations of azaprophen

Proc. ISBBP Symposium Biochem.Biophysics (Karachi)1: 82-84

S. Hashim, K. Parveen and M. A. Haleem (1994)

Potential energy calculations of 2-(α-d-2-deoxyribofuranosyl) maleimide

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1: 85-87

K. Saboohi, T. Mahboob and M. A. Haleem (1994)

Effect of 2% KCl on serum and red cell sodium and potassium.

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1: 88-89

T. Mahboob and M. A. Haleem (1994)

Changes in red blood cell sodium and potassium as a predictor of caffeine-induced hypertension in rats.

Proc.ISBBP Symposium Biochem.Biophysics (Karachi) 1: 91-94

M. Zehra, N. Akhter, I. M. Kidwai and M. A. Haleem (1994)

Conformational studies of Gallamine Triethiodide: a neuromuscular blocking agent

Proc.ISBBP Symposium Biochem.Biophysics ( Karachi) 1: 99-102

F. Zaheer, N. Akhter, I. M. Kidwai, Z. A. Saify and M. A. Haleem (1994)

Conformational analysis of Loxapine: a psychoactive drug.

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1: 127-130

Z. Fatima, T. Mahboob and M. A. Haleem (1994)

Alterations in serum electrolytes after indomethacin and acute sodium chloride load: a sex related study.

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1, 136-139

S. Zafar, T. Mahboob and M. A. Haleem (1994)

Electrolyte Alterations after acute ethanol administration: a sex related study.

Proc. ISBBP Symposium Biochem.Biophysics (Karachi)1, 155-157

T. Syeda, D. J. Haleem and M. A. Haleem (1994)

Injected tryptophan increases plasma, liver and brain tryptophan more in ethanol treatred rats.

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1, 162-164

M. A. Haleem, F. Deeba and Naheed Akhter (1994)

Computational studies on the structure of cellulose II

Proc. ISBBP Symposium Biochem.Biophysics (Karachi) 1, 165-168

J. Ara, M. A. Haleem and A. Zia-ul-Haq (1994)

Effect of indomethacin on serum electrolytes, osmomolality and hematocrit in rabbits.

Proc. 2nd national Biochem symposium, (Karachi) pp.71-80

S. Zafar, T. Mahboob and M. A. Haleem (1994)

A Sex-related study of serum electrolytes after the administration of aspirin.

Proc. 2nd national Biochem. Symposium,( Karachi) pp.395-400

M.Ismail,N.Akhtar,I.M.Kidwai and M.A.Haleem (1994)

Potential energy calculations of (Rs)-1,4-dibenzoyl-cis-2,5 dimethyl piperazine

Kar.Univ.J.Sc. 22(1&2):101-107.

K.Perveen,N.Akhtar, I.M.Kidwai and M.A.Haleem.(1993):

Potential energy calculations of metyrapone.

Kar.Uni.J.Sc.,21(1‑2):201‑205.

Tabassum M. and M.A.Haleem.(1993):

Correlation between concentration of magnesium,sodium,potassium and calcium in plasma and tissues of ethanol treated rats in: Role of magnesium and trace elements ,New Dehli, India

Edited by R.Nath and K.D.Gill ,pp.137‑140.

S.Iftikhar ,T.Mehboob and M.A.Haleem.(1993):

Alternations in serum electrolytes after indomethan administration:A sex related study.

Pak.J.Pharmacol.10(1):47‑53.

Tabassum M. and M.A.Haleem. (1993):

Caffeine consumption and blood pressure in rats: Role of intracellular electrolyte alternations.

in:Ist.Int.Conf.on the impact of food research on new product development.

ed:R.Ali and P.J.Barlow ,published by Univ. Of Humberside,U.K.,pp 134-141

M.K.Azim, Naheed Akhtar and M.A.Haleem.(1993):

Computer aided conformational analysis of psychoactive agent: amoxapine.

in: 2nd.Nat.Biochem.Sym.,Hyderabad,Pakistan.,pp.9.

Samina Bano and M.A.Haleem .(1993):

Inhibition of tryptophan pyrrolase activity in monosodium glutamate injected rats.

in: 2nd.Nat.Biochem.Sym.,Hyderabad,Pakistan.,pp.13.

Shela Z.K.and M.A.Haleem. (1993):

Effect of various doses of aspirin on serum electrolyte and osmolality.

in:2nd nat.Biochem.Sym.,Hyderabad,Pakistan.,pp,15.

Tabassum Mehboob and M.A.Haleem.(1993):

Ethanol induced hypertentsion: Correlation between concentration of magnesium, sodium, potassium and calcium in plasma, heart, liver and kidney tissues of chronic ethanol treated rats.

in :2nd Nat.Biochem.Sym.Hyderabad,Pakistan.,pp.43.

Jehan Ara.T.Mehboob,D.J.Haleem and M.A.Haleem.(1993):

Sex dependent studies on the effect of monosodium glutamate on electrolytes and osmolality in rats. in : 2nd Nat.Biochem.Sym.Hyderabad,Pakistan.,pp.12.

A. Khatoon, N. Akhter, I.M. Kidwai and M. A. Haleem (1993)

Potential energy calculations of methyl-α-thiomaltoside

Pak. J. Scie. Ind. Res. 36(12): 517-519.

T.F.Moazzam,Tabassum Mahboob,T.M.Ali and M.A.Haleem (1992):

Effect of MSG on serum electrolytes in rabbits.

Pak.J.Pharmacol.,9(2):23-28

Tahira Perveen, M.A. Haleem and Darakhshan J. Haleem. (1992)

Effect of adrenaline and noradrenaline on brain serotonin.

Pak. J. Pharmacol. 9(1): 75‑83.

Jehan Ara,Darakhshan J.H.,T.Mehboob T., and M.A.Haleem.(1992):

Acetylsalicylate a non‑steroidal anti‑inflammatory drug increases serum electrolytes concentration more in male than female rats in: Proc. Ist. Nat. Biochem. Sym., Karachi, Pakistan.e pp. 15‑20.

T.Mehboob,Darakhshan J.Haleem and M.A.Haleem.(1992):

Alcohol induced hypertension:A possible role of electrolytes alterations.

in:Proc.Ist.Nat.Biochem.Sym., Karachi, Pakistan.

ed: S.N.Hasnain,M.A. Haleem,H.S.A. Athar, pp. 21‑26.

Samina Bano,M.A.Haleem and Darakhshan J.Haleem.(1992):

Attenuation of brain serotonin metabolism in monosodium glutamate injected rabbits: A possible role of increased liver tryptophan pyrrolase activity.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan.

ed: S.N. Hasnain,M.A. Haleem, H.S.A. Athar,pp 33‑37.

Tahira Perveen,M.A.Haleem and Darakhshan J.Haleem.(1992):

Adrenaline and nor‑adrenaline enhance brain serotonin metabolism by increasing serum free but not total tryptophan.in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan.ed: S.N. Hasnian, M.A. Haleem, H.S.A. Athar, pp. 38‑42.

T.Fatema,T.Mehboob ,T.M.Ali Khan and M.A.Haleem.(1992):

Effect of monosodium glutamate on serum electrolytes in rabbits.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan. ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp. 72‑76.

K.Perveen,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992):

Potential energy calculations of metyrapone.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan.ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,pp.

125‑129.

Farhat Deeba,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992):

Studies on the structure of cellulose II

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan. ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp. 141‑146

M.A.Haleem and N.Akhtar .(1992):

Refinement of triple helical structure of β‑D‑1,3 xylan.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan.ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp. 130‑134.

N.Akhtar and M.A.Haleem.(1992):

Studies on the structure of β‑chitin.

in:Proc.Ist.Nat.Biochem.Sym., Karachi, Pakistan ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp 113‑119.

M. Ismail, Naheed Akhter, I.M. Kidwai and M. A. Haleem (1992)

Potential energy calculations of 2-formyl-4-morpholino pyridinethio semicarbazone as an-antitumor drug.

Pak. J. Pharmacol, 9(1) 41-44

Noor Jehan,N.Akhtar,I.M.Kidwai and M.A.Haleem.(1992):

Potential energy calculations of 2‑formyl‑4‑morpholino‑pyridine thio semicarbazone.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan.ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp 120‑124.

Meena Merchant, Zafar S.Saify and M.A.Haleem.(1992):

Potential energy calculations of nalbuphine hydrochloride.

in:Proc.Ist.Nat.Biochem.Sym.,Karachi, Pakistan. ed: S.N. Hasnain, M.A. Haleem, H.S.A. Athar,

pp. 135‑140.

Tabassum Mehboob and M.A.Haleem.(1992):

Changes in blood pressure and electrolyte content after invivo acute sodium load.

in Proc.Ist.Int.Conf.Pharamceutical Sc. (Karachi)pp.44

M.A.Haleem,Meena Merchant and Z.S.Saify.(1992):

Conformational analysis of psychoactive drugs.

in: Proc.Ist.Conf.Pharmaceutical Science.(Karachi) ,pp.23

N.Akhtar and M.A.Haleem (1992):

Rigid refinement of triple helical structure of β-D-1,3 xylan

in.Proc.Ist.Int.Conf. of Pharmaceutical Sciences.Karachi.

pp.23.

Tabassum Mehboob,Sirajuddin and M.A.Haleem (1991)

Effect of adrenaline on serum and tissue electrolytes.

Pak.J.Pharmacol., 8(1&2):31‑36.

M.Ismail ,Naheed Akhtar,I.M.Kidwai and M.A.Haleem.(1991):

Potential energy calculations of 2‑formyl‑4‑morpholino pyridine thio semicarbazone as an anti tumor drug.

Pak.J.Pharmacol., 9(1): 41‑44.

Ateeq Farhana,Naheed Akhtar,I.M.Kidwai and M.A.Haleem.(1991):

Studies on the structure of β‑chitin.

in:International sym.on contemp.biol.,Islamabad.,pp.103.

Jehan Ara,Darakhshan J.H.,Tabassum.M.and M.A.Haleem.(1991):

Sex differences in the effect of indomethacin on electrolyte balance and osmolality.

Int.Sym.on Contem.Biology., Islamabad. pp.26.

Tabassum Mehboob and M.A.Haleem.(1991):

Altered elements in tissues of alcohol induced hypertensive rats.

Int.Sym.on Contemp.Biology., Islamabad. pp.100.

Naheed Akhtar and M.A.Haleem (1990):

Studies on the structure of β‑chitin:

Z.Naturforsch.,45b:87‑92

Tabassum Mahboob and M.A. Haleem. (1989):

Effect of NSAIDS on serum electrolytes and osmolality

Life Sciences (USA)., 45(6) : 499‑507. 2.7 Impact Factor

M.A. Haleem, Meena Ramzan Ali and Zafar Saeed Saify.(1989):

Potential energy calculations of piperx and dextimide

Pak. J. Sc. Ind. Res., 32(2) : 76‑78.

M.A. Haleem and Zafar S. Saify (1989) :

Potential energy calculations of treptilaminum:An anticholinergic drug.

Pak. J. Sc. Ind. Res., 32(2) : 74‑75.

Tabassum Mehboob and M.A.Haleem (1989):

Effect of aldosterone on serum electrolytes:

Proc.Natl.Chem.Conf.1: 349‑353.

Tabassum Mehboob and M.A.Haleem (1989):

Effect of vasopressin administration on serum electrolytes and osmolality.

In:Trace 89 (Proceedings of 3rd.International congress trace elements in health and disease at Adana,Turkey)

Ed: G.T.Yuregir,Orkida Donma and Levent Kayrin,pp.299‑302

Tabassum Mahboob and M.A. Haleem (1988):

Effect of ethanol on serum electrolytes and osmolality.

Life Sciences. 42(16): 1507‑15

2.7 Impact Factor

M.A. Haleem, Meena Ramzan Ali and Zafar S. Saify (1988):

Potential energy calculations of nalbuphine hydrochloride.

Pak. J.Sc.Ind.Res. 31(5) : 330‑333.

Zafar S. Saify and M.A. Haleem. (1988):

Conformational studies on the structure of 19‑propyl thevinol hydrobromide.

Pak. J. Sc. Ind. Res. 31(4) : 245‑247

Abdur Rehman Siddiqui, Darakhshan J. Haleem and M.A. Haleem.(1988):

Effect of glucose on the distribution of tryptophan in serum liver and brain.

Pak. J. Sc. Ind. Res. 31(5) : 349‑351.

Tahira Perveen, Darakhshan J. Haleem and M.A. Haleem. (1988):

Effect of ethanol on brain and hepatic tryptophan metabolism in rabbit.

Pak. J. Sc. Ind. Res. 31(5) : 346‑348.

M.A. Haleem, Meena Ramzan Ali and Zafar Saeed Saify. (1988):

Potential energy calculations of metyrapone.

Pak. J. Sc. Ind.Res., 31(10): 687‑689.

Saida Haider and M.A. Haleem. (1988) :

Effect of aspirin on serum electrolytes in Rabbits.

Pak. J. Pharmacol., 5(2) : 49‑53.

Tabassum,M. and M.A.Haleem., (1987).

Effect of MSG (monosodium glutamate) on serum electrolytes and osmolality

in: praceedings of second international conference on elements in health and disease , Karachi Pakistan.

Edited by: Saeed,M., Ataur‑Rehman, M., Lily Anne D’Silva pp. 231‑236.

M.A. Haleem & Zafar S. Saify. (1986).

Preferred conformation of m‑Nitrophenyladmantyl piperidine on the basis of potential Energy Calculations.

Pak. J. Sc. Ind. Res., 29(1) : 19‑22.

Naheed Akhtar and M.A. Haleem. (1985):

Studies on the structure of α‑chitin. 3rd International conference on chitin and chitosan (ITALY).

M.A. Haleem & Salma Qamruddin. (1985):

Studies on Triple helical structure of β‑ D‑1,3 xylan.

Z.Naturforsch., 40c : 751‑754

Zakia Sultana, Darakhshan J.H.and M.A. Haleem, (1985)

Free and bound Riboflavin content in various tissues of a Desert Lizard.

Pak. J. Biochemistry., Vol. XVIII. (1‑2) : 1‑3.

Rafat Ali Siddiqui, Darakhshan J.H., & M.A. Haleem (1984):

Effect of drugs on the distribution of tryptophan in plasma,liver and brain in a desert lizard.

Pak. J. Biochem., XVII(1‑2) : 39‑43.

Darakhshan J.H., M.A. Haleem & S.N. Hasnain. (1984) :

Effect of chronic ethanol administration on distribution of tryptophan in apo‑tryptophan pyrrolase lacking species.

Pak. J. Sc. Ind. Res., 27(5) : 267‑270.

Darakshan Jabeen & M.A. Haleem. (1980):

Binding of L‑tryptophan with Human serum albumin.

Pak. J. Biochem., 13(1) : 18‑21.

Darakshan Jabeen & M.A. Haleem. (1979):

Hibernational changes of tryptophan in Uromastix hardwickii.

Pak. J. Biochem., 12(1): 43‑45.

Darakhshan Jabeen & M.A. Haleem. (1978):

Seasonal variation of tryptophan in Uromastix hardwickii. Pak. J. Zoo., 2(10): 300‑302

M.A. Haleem & K.D. Parker. (1977):

Studies on the helical structure of β‑D‑1,3 xylan.

Z.Naturforsch., 32c : 665‑668.

1.195 Impact Factor (1992)

M.A. Haleem & K.D. Parker. (1977):

Scattering of X‑rays by parallel and antiparallel layers in disordered stacking and statistical layer shift for α‑chitin. Z.Naturforsch., 32c : 669‑671 1.195 Impact Factor (1992)

Darakhshan Jabeen & M.A. Haleem. (1977): Displacement of tryptophan from it binding sites by sodium salicylate.

Pak. J. Sc. Ind. Res., 20(6) : 343‑345

M.A. Haleem and K.D. Parker, (1976):

X‑ray diffraction studies on the structure of α‑chitin.

Z.Naturforsch., 31c : 383‑388.

1.195 Impact Factor

Darakhshan Jabeen & M.A. Haleem. (1976):

Interaction of riboflavin with aromatic aminoacids.

Pak. J. Biochem., 9 (1) : 20‑2

S.M. Pervaiz and M.A. Haleem. (1975):

Studies on the structure of β‑chitin, I.

Z.Naturforsch., 30c : 571‑574.